Poor periodontal health of pregnant women as a risk factor for preterm and low birth weight
Article Outline
Abstract
Background
Preterm delivery of low birth weight infants remains a significant public health issue and a leading cause of neonatal death, long term neurodevelopmental disturbances, and health problems. Several recent studies have suggested a relationship between preterm delivery and periodontal disease. The aim of the study was to determine the association between maternal periodontitis and pre-term/low birth weight (PLBW).
Method
The case-control study included 400 patients between the age group of 18–35 years. The mothers were categorized based on the weight of the infants as cases (<2500 g and <37 weeks) and controls (≥2500 g and ≥37 weeks). The associated risk factors for periodontal diseases and PLBW like age of mother, literacy status, hemoglobin levels, history of previous deliveries, history of previous PLBW deliveries, history of dental treatment, and periodontal status were ascertained by means of structured questionnaires and maternity case records. Periodontal parameters were assessed using the community periodontal index (CPI).
Results
The risk factors significantly associated with PLBW are literacy status of the mother (χ2 = 17.062, p < 0.001), hemoglobin level of the mother (χ2 = 55.62, p < 0.0001), history of previous PLBW deliveries (χ2 = 102.797, p≤0.0001), and CPI scores (χ2 = 83.28, p < 0.0001).
Conclusion
Our findings showed an association of periodontal disease with PLBW as an independent risk factor. Thus, it remains important to promote good oral hygiene during routine prenatal visits during pregnancy.
Keywords: Low birth weight , periodontitis , preterm
No full text is available. To read the body of this article, please view the PDF online.
References
- Potential pathogenic mechanisms of periodontitis associated pregnancy complications . Ann Periodontol . 1998;3:233–250
- . Effects of E. coli and P. gingivalis lipopolysaccharides on pregnancy outcome in the golden hamster . Infect Immun . 1994;62:4652–4655
- . Poor periodontal health of the pregnant woman as a risk factor for low birth weight . Ann Periodontol . 1998;3:206–212
- . The East London study of maternal chronic periodontal disease and preterm low birth weight infants: study design and prevalence data . Ann Periodontol . 1998;3:213–221
- . Idiopathic preterm deliveries in Denmark . Obstet Gynecol . 1995;86:800–804
- . In: Preterm Labour . Churchill Livingstone Publishing; 1997;p. 11–19
- . Anemia and spontaneous preterm birth . Am J Obstet Gynecol . 1991;164(1 Pt 1):59–63
- . Risk factors associated with the occurrence of preterm birth . Clin Obstet Gynecol . 1984;27:539–552
- . Cytokine abundance in placental tissues: evidence of inflammatory activation in gestational membranes with term and preterm parturition . Am J Obstet Gynecol . 1999;181:1530–1536
- Detection of porphyromonas gingivalis in the amniotic fluid in pregnant women with a diagnosis of threatened premature labor . J Periodontol . 2007;78:1249–1255
- . Persistently high levels of periodontal pathogens associated with preterm pregnancy outcome . J Periodontol . 2007;78:833–841
- . Periodontitis as a risk factor for preterm low birth weight . Yonsei Med J . 2008;49:200–203
- . Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial . J Periodontol . 2002;73:911–924
PII: S0975-962X(11)60032-4
doi:10.1016/S0975-962X(11)60032-4
© 2011 Gian Sagar Dental College & Hospital. Published by Elsevier Inc. All rights reserved.
