Indian Journal of Dentistry
Volume 2, Issue 2 , Pages 11-15, June 2011

Efficacy of two different concentrations of chlorhexidine mouth-rinse on plaque re-growth

  • Daljit Kapoor, MDS

      Affiliations

    • Professor and HOD, Department of Periodontology, Gian Sagar Dental College and Hospital Ramnagar, Rajpura, India
    • Corresponding Author InformationCorrespondence: Dr. (Mrs) Daljit Kapoor, Professor and HOD, Department of Periodontology, Gian Sagar Dental College and Hospital
    • ,
  • Navjot Kaur, MDS

      Affiliations

    • Senior Lecturer, Department of Periodontology, Bhojia Dental College, Baddi (Solan)
    • ,
  • Tarun Nanda, MDS

      Affiliations

    • Senior Lecturer, Department of Periodontology, Gian Sagar Dental College and Hospital Ramnagar, Rajpura, India

Received 10 April 2011; accepted 16 May 2011.

Article Outline

Abstract 

Background

Numerous locally active antimicrobial substances are intended to prevent or reduce the formation of dental plaque. Chlorhexidine digluconate has been proved to be the most effective anti-plaque agent so far by various investigators, either combined with other ingredients or as a positive control.

Materials and Method

A total of 30 dental interns, whose plaque scores were brought to zero, were evaluated for plaque re-growth. They were instructed to rinse twice daily with commercially available 0.2% and/or 0.12% chlorhexidine digluconate mouthwash for 4 days and to refrain from all other mechanical oral hygiene measures.

Results

Both preparations of chlorhexidine were found to be almost equally effective for their plaque inhibiting capacity. No statistically significant difference was observed for both preparations.

Conclusion

From the present clinical trial, it was observed that both the preparations of chlorhexidine digluconate mouth rinse were almost similar in their efficacy in terms of their plaque inhibiting capacity.

Keywords:  Chlorhexidine , plaque re-growth , substantivity

No full text is available. To read the body of this article, please view the PDF online.

 

Back to Article Outline

References 

  1. Zanatta FB , Antoniazzi RP , Rosing CK . The effect of 0.12% chlorhexidine gluconate rinsing on previously plaque-free and plaque-covered surfaces-a randomized controlled clinical trial . J Periodontol . 2007;78:2127–2134
  2. Lovdal A , Arno A , Schei O , Waerhaug J . Combined effect of subgingival scaling and controlled oral hygiene on the incidence of gingivitis . Acta Odontol Scand . 1961;19:537–555
  3. Axelsson P , Lindhe J . Effect of oral hygiene instruction and professional tooth cleaning on caries and gingivitis in school children . Community Dent Oral Epidemiol . 1981;9:251–255
  4. Rodrigues JA , dos Santos PA , Garcia PP , Corona SA , Loffredo LC . Evaluation of motivation methods used to obtain appropriate oral hygiene levels in school children . Int J Dent Hyg . 2003;1:227–232
  5. Kalaga A , Addy M , Hunter B . The use of 0.2% chlorhexidine spray as an adjunct to oral health in physically and mentally handicapped adults . J Periodontol . 1989;60:381–385
  6. Roberts WR , Addy M . Comparison of the in-vivo and in-vitro antibacterial properties of antiseptic mouth-rinses containing chlorhexidine, alexidine, cetyl pyridinium chloride and hexitidine. Relevance to mode of action . J Clin Periodontol . 1981;8:295–310
  7. Rolla G , Melsen B . On the mechanism of the plaque inhibition by chlorhexidine . J Dent Res . 1975;54:57–62
  8. Hugo WB , Longworth AK . Some aspects of the mode of action of chlorhexidine . J Pharm Pharmacol . 1964;16:655–662
  9. Arweiler NB , Boehnke N , Sculean A , Hellwig E , Auschill TM . Differences in efficacy of two commercial 0.2% chlorhexidine mouthrinse solutions: a 4-day plaque re-growth study . J Clin Periodontol . 2006;33:334–339
  10. Fine DH . Chemical agents to prevent and regulate plaque development . Periodontol 2000 . 1995;8:87–107
  11. Siegriest BE , Gusberti FA , Brecx MC , Weber HP , Lang NP . Efficacy of supervised rinsing with chlorhexidine digluconate in comparison to phenolic plant alkaloid compounds . J Perio Rest . 1986;21:60–73
  12. Moran J , Addy M , Newcombe R . A clinical trial to assess the efficacy of sanguinarine-zinc mouth rinse (Veadent) compared with chlorhexidine mouth rinse (Corsodyl) . J Clin Periodontol . 1988;15:612–616
  13. Loe H , Theilade E , Jensen SB . Experimental gingivitis in man . J Periodontol . 1965;36:177–187
  14. Suomi JD , Smith LW , McClendon BJ . Marginal gingivitis during a sixteen week period . Journal of Periodontolgy . 1971;42:268–270
  15. Axelsson P , Lindhe J . The effect of a preventive programme on dental plaque, gingivitis and caries in schoolchildren. Results after one and two years . J Clin Periodontol . 1974;1:126–138
  16. Axelsson P , Lindhe J . Effect of controlled oral procedures on caries and periodontal disease in adults . Journal of Clinical Periodontology . 1978;5:133–151
  17. Lindhe J , Karring T , Lang NP . In: Clinical Periodontology and Implant Dentistry . 4th ed.. Copenhagen: Munskgaard; 2003;p. 476–481
  18. Loe H , Schiott CR . The effect of mouth-rinses and topical application of chlorhexidine on the development of dental plaque and gingivitis in man . J Periodontal Res . 1970;5:79–83
  19. Segreto VA , Collins EM , Beiswanger BB , et al.   A comparison of mouthrinses containing two concentrations of chlorhexidine . J Periodont Res . 1986;21(Suppl 16):23–32
  20. Schiott C , Loe H , Jensen SB , Kilian M , Davier RM , Glavind K . The effect of chlorhexidine mouthrinses on the human oral flora . J Periodontol Res . 1970;5:84–89
  21. Barkvoll P , Rolla G , Svendsen A . Interaction between chlorhexidine digluconate and sodium monofluorophosphate in vitro . Scandanavian J Dent Res . 1989;96:30–33
  22. Addy M , Willis L , Moran J . Effect of toothpaste rinses compared with chlorhexidine on plaque formation during a 4-day period . J Clin Periodontol . 1983;10:89–99
  23. Jones CG . Chlorhexidine: is it still the gold standard? . Periodontol 2000 . 1997;15:55–62
  24. Stoeken JE , Versteeg PA , Rosema NA , Timmerman MF , van der Velden U , van der Weijden GA . Inhibition of “de novo” plaque formation with 0.12% chlorhexidine spray compared to 0.2% chlorhexidine mouthwash . J Periodontol . 2007;78:899–904
  25. Hull PS . Chemical inhibition of plaque . J Clin Periodontol . 1980;7:431–442
  26. Keijser JA , Verkade H , Timmerman MF , van der Weijden FA . Comparison of 2 commercially available chlorhexidine mouth-rinses . J Periodontol . 2003;74:214–218
  27. Smith RG , Moran J , Addy M , Doherty F , Newcombe RG . Comparative staining in vitro and plaque inhibitory properties in vivo of 0.12% and 0.2% chlorhexidine mouth-rinses . J Clin Periodontol . 1995;22:613–617
  28. Addy M , Moran J , Newcombe  . A comparison of 0.12% and 0.1% chlorhexidine mouthrinse on the development of plaque and gingivitis . Clin Prev Dent . 1991;13:26–29

PII: S0975-962X(11)60004-X

doi:10.1016/S0975-962X(11)60004-X

Indian Journal of Dentistry
Volume 2, Issue 2 , Pages 11-15, June 2011

Article Tools